Radiosurgery - a method of high-precision single irradiation of intracranial pathologic focus, using a large dose of radiation, using a stereotactic technique through the intact skull. The first installation of the gamma knife developed Lars Leksell. Being engaged in treating Parkinson's disease and epilepsy, he created a stereotactic frame of its own design for high precision neurosurgical procedures. Later developed a prototype gamma knife sources Cobalt 60. Efficacy and safety of treatment confirmed by long periods of observation and are reflected in numerous publications. Because of its accuracy, and effectiveness of Gamma Knife recognized "gold standard" in radio-surgery. Building on the target structure occurs with an accuracy of 0.5 mm in the automatic mode, which eliminates the risk of errors. Strong radiation causes damage to the DNA of pathological cells, therefore violated the uncontrolled growth of tumors. Treatment is carried out for one procedure and usually takes several hours. Treatment of Gamma-knife is absolutely painless and does not require general anesthesia. There is no skin incision, in most cases, patients return to their daily activities the next day after surgery. The indications for radio-surgery gamma knife are: brain metastases, trigeminal nerve neurinomas of the auditory nerve; pituitary adenoma, arteriovenous malformations and cavernous angioma, meningioma, primary brain tumor. The main limitation for the operation of the Gamma knife is the maximum size of the tumors over 30 mm. Advantages of the "Gamma Knife" derived from its Non-invasive. For no treatment is necessary in the long pre-operative preparation, and that much more important in the postoperative treatment and rehabilitation. There is no risk of bleeding and infection. There is no risk of general anesthesia. On the gamma-knife treatment may be multiple entities. Perhaps the safe treatment of formations located in deep brain structures and on the basis of the skull. Perhaps treatment of tumor recurrence after the operation and radiotherapy.